Neuronal inclusions

Neuronal inclusions are abnormal clumps or deposits of proteins that form inside nerve cells. They often develop when certain proteins misfold or are not properly cleared, disrupting normal cell functions. These inclusions are commonly associated with neurodegenerative diseases like Alzheimer's and Parkinson's, where they can impair communication between neurons and contribute to cell death. While their presence can be a hallmark of disease, their exact role varies and is an area of ongoing research to better understand how they influence brain health.