Neuromuscular Junction Disorders

Neuromuscular Junction Disorders (NMJ disorders) are conditions that affect the communication between nerves and muscles, leading to muscle weakness and fatigue. In a healthy NMJ, nerve signals prompt muscles to contract. However, in disorders like myasthenia gravis, the body’s immune system mistakenly attacks the NMJ, disrupting this communication. Symptoms can include drooping eyelids, difficulty swallowing, and overall muscle weakness, often worsening with activity. Diagnosis typically involves blood tests and electromyography, while treatment may include medications, therapies, or lifestyle adjustments to help manage symptoms and improve muscle function.