Neoantigens

Neoantigens are unique protein fragments that arise from genetic mutations within cancer cells. Because these mutations are not present in normal cells, neoantigens can be recognized by the immune system as foreign, triggering an immune response. This makes neoantigens important targets for cancer immunotherapy, as they help the immune system distinguish and attack cancer cells specifically, while sparing healthy cells. Understanding neoantigens is key to developing personalized cancer treatments that harness the body's immune defenses to fight specific tumors more effectively.