NaV1.5 (Sodium Channel, Alpha Subunit)

NaV1.5 is a specific type of sodium channel found primarily in the heart's muscle cells. It is a protein that forms a channel allowing sodium ions to enter the cells, which is essential for generating electrical signals that control the heartbeat. This channel opens and closes in response to electrical stimuli, helping regulate the heart's rhythm and contractions. Proper functioning of NaV1.5 is crucial; mutations can lead to heart rhythm disorders such as arrhythmias, affecting how effectively the heart pumps blood. It is a key component in maintaining normal cardiac electrical activity.