Nav1.4

Nav1.4 is a specific type of sodium channel found mainly in skeletal muscle cells. It functions as a gate that opens to allow sodium ions to enter the muscle fibers when the cell needs to generate a muscle contraction. This process is essential for normal muscle movement. Mutations or problems with Nav1.4 can lead to muscle disorders, such as periodic paralysis or myotonia, affecting strength and coordination. Overall, Nav1.4 plays a critical role in translating nerve signals into the physical action of muscles.