Native PAGE

Native PAGE (Polyacrylamide Gel Electrophoresis) is a laboratory method used to separate proteins based on their size and shape while keeping their natural structure intact. Unlike other methods that denature proteins, Native PAGE preserves their functional form, allowing researchers to study their activity, interactions, and complexes. The process involves applying a protein mixture to a gel and applying an electric current, causing proteins to migrate at different rates depending on their properties. It’s a useful technique for analyzing proteins in their natural state for research and diagnostic purposes.