NARP syndrome

NARP syndrome (Neurogenic Myopathies with Ataxia and Retinitis Pigmentosa) is a rare genetic disorder caused by mutations in mitochondrial DNA. It affects how cells produce energy, leading to a gradual decline in muscle strength, coordination (ataxia), and vision problems, especially difficulty seeing in low light. Symptoms typically appear in adolescence or early adulthood and progress over time. The condition primarily impacts the nervous system, muscles, and eyes, resulting in weakness, balance issues, and vision loss. NARP is inherited maternally, as mitochondria are passed from mother to child. There is no cure, but management focuses on symptom relief and supportive care.