
N-terminal propeptide of type I collagen (P1NP)
N-terminal propeptide of type I collagen (P1NP) is a small protein fragment released when the body produces type I collagen, the main protein in bones, skin, and tendons. It serves as a marker to measure how actively the body is forming new collagen and, consequently, building new bone tissue. Elevated P1NP levels can indicate increased bone formation, while lower levels may suggest decreased bone activity. This measurement helps doctors assess bone health, monitor osteoporosis treatment, and understand processes related to bone growth or loss.