Myosin light chain kinase

Myosin light chain kinase (MLCK) is an enzyme that plays a key role in muscle contraction and other cellular movements. It works by adding phosphate groups to the myosin protein’s light chains, which activates myosin. This activation allows myosin to interact with actin, another protein, to generate movement or force within the cell. MLCK is especially important in smooth muscles, like those in blood vessels or the digestive system, helping regulate functions such as blood flow or gut motility. Its activity is controlled by signals like calcium levels, ensuring precise regulation of muscle actions.