Myeloid-derived suppressor cells (MDSCs)

Myeloid-derived suppressor cells (MDSCs) are a group of immune cells that naturally develop in the body, especially during illnesses like cancer or infections. Their primary role is to regulate the immune system by preventing it from overreacting. However, in some conditions like cancer, MDSCs can become overly active, suppressing the body’s ability to attack tumors. This makes them important in understanding disease progression and developing treatments. Essentially, MDSCs act as a balancing force in the immune system but can be hijacked by diseases to help them evade immune defenses.