Multicentric Castleman Disease

Multicentric Castleman Disease (MCD) is a rare disorder where abnormal growth of lymph nodes occurs across multiple regions of the body. This leads to symptoms like enlarged lymph nodes, fever, night sweats, fatigue, and weight loss. It involves excessive immune system activity that causes inflammation and can affect organs. The exact cause isn’t fully understood, but infection with certain viruses or immune dysregulation may play a role. MCD requires medical management, often involving therapies that target immune system activity or specific cellular factors. Early diagnosis and treatment are important for controlling symptoms and preventing complications.