Mosaicism

Mosaicism occurs when a person has two or more populations of cells with different genetic makeup, all originating from a single fertilized egg. This means some cells have typical DNA, while others have genetic variations or mutations. These differences can affect how the body develops and functions, often leading to varied health features within the same person. Mosaicism can be limited to specific tissues or widespread, depending on when the genetic change happens during cell development. Understanding mosaicism helps explain why some genetic conditions or traits appear differently, even within the same individual.