
Misfolded protein aggregation
Misfolded protein aggregation occurs when proteins in the body fold incorrectly and stick together, forming clumps. Normally, proteins fold into specific shapes to perform their functions properly. When they misfold, they can stick together and form aggregates that disrupt cell activity. This process is linked to several diseases, such as Alzheimer's and Parkinson's, where these protein clumps damage brain cells. Factors like genetic mutations, aging, or environmental stresses can increase the likelihood of misfolding. Understanding and preventing protein aggregation is a key area of research aimed at treating or slowing these neurodegenerative diseases.