MERFISH

MERFISH (Multiplexed Error-Robust Fluorescence In Situ Hybridization) is a powerful imaging technique used to map the locations and types of thousands of individual RNA molecules within cells. It uses specially designed fluorescent probes that attach to specific RNA sequences, allowing scientists to identify and count many different genes simultaneously. By doing so, MERFISH provides detailed, high-resolution snapshots of gene activity inside cells, helping researchers understand where and how genes are expressed. This method combines advanced microscopy with clever data encoding to provide comprehensive insights into cellular function and organization.