MEN1 mutation

MEN1 mutation refers to a change in the MEN1 gene, which produces a protein called menin that helps regulate cell growth. When this gene is mutated, its function is impaired, leading to a higher risk of developing tumors in endocrine glands like the parathyroids, pituitary, and pancreas. This inherited mutation causes Multiple Endocrine Neoplasia Type 1 (MEN1), a hereditary condition where these tumors can cause various hormonal imbalances and health issues. Early detection and management are important to monitor and treat these tumors effectively.