MEN1 gene

The MEN1 gene provides instructions for producing a protein called menin, which helps regulate cell growth and division. When the MEN1 gene has mutations, it can disrupt this control, leading to the development of tumors in multiple endocrine glands such as the pancreas, parathyroids, and pituitary. These tumors can cause various hormonal imbalances and health issues. MEN1 gene mutations are inherited and can increase the risk of multiple endocrine tumors, making genetic testing important for diagnosis and management of affected individuals.