MEK (MAPK/ERK kinase)

MEK (MAPK/ERK kinase) is a protein within cells that plays a key role in a signaling pathway called the MAPK/ERK pathway. This pathway transmits signals from the cell surface to the nucleus, influencing cell growth, division, and survival. MEK acts as an intermediary, activating another protein called ERK, which then affects gene expression and cellular behavior. Proper functioning of MEK is essential for normal cell processes, but when it's overactive or mutated, it can contribute to uncontrolled cell growth, a hallmark of cancer. Therefore, MEK is a significant target in certain cancer therapies.