Management of graft-versus-host disease in children

Management of graft-versus-host disease (GVHD) in children involves controlling the immune response to prevent damage to healthy tissues. Treatment typically includes immunosuppressant medications to dampen the immune attack, such as corticosteroids. Supportive care is also essential, including antibiotics to prevent infections, skin care, and nutrition support. Monitoring is crucial to detect and manage side effects or complications early. In some cases, additional therapies like growth factors or newer targeted drugs are used. The goal is to reduce GVHD severity while maintaining the transplanted cells' ability to fight disease, ensuring the child's safety and recovery.