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mammalian cell gene mutation test

The mammalian cell gene mutation test assesses how certain substances might cause genetic changes in mammalian cells. By exposing cultured cells to a chemical and then analyzing them, scientists can identify whether the substance induces mutations—changes in the cell's DNA. This test helps evaluate potential genetic hazards, such as cancer risk. It provides insights into whether a chemical has mutagenic (mutation-causing) properties, informing safety assessments and regulatory decisions to protect human health and the environment.