lysosomal biogenesis

Lysosomal biogenesis is the process by which cells produce and maintain lysosomes, specialized structures that break down waste materials, worn-out cell parts, and various biological molecules. This process involves the synthesis of lysosomal enzymes and membrane components in the endoplasmic reticulum, followed by their transport to the Golgi apparatus. From there, they are packaged into vesicles that mature into lysosomes. Proper lysosomal biogenesis ensures efficient cellular cleanup and recycling, critical for cell health and function. Disruptions in this process can lead to accumulation of waste and are associated with certain diseases.