lupus nephritis class system

Lupus nephritis is a kidney inflammation caused by lupus, classified into six groups based on kidney tissue changes seen under a microscope. These classes range from I (minimal change) to VI (advanced scarring). Classes I and II involve mild inflammation, often with little damage, while Classes III and IV are more severe, with inflammation and possible loss of kidney function. Class V, membranous lupus, involves thickening of kidney membranes, and Class VI indicates advanced scarring. This classification helps doctors determine severity and guide treatment strategies for better management of kidney involvement in lupus.