Local Assembly

Local assembly is a process in genome sequencing where small sections of DNA, called contigs, are pieced together into longer, continuous sequences within specific regions of a genome. Instead of assembling the entire genome at once, local assembly focuses on smaller areas, which helps resolve complex or repetitive parts more accurately. Think of it like assembling individual puzzle sections to clarify difficult spots before combining everything into the full picture. This approach improves the quality and accuracy of the final genome sequence, especially in challenging or highly variable regions.