LKB1 (STK11)

LKB1, also known as STK11, is a gene that produces a protein functioning as a master regulator for maintaining healthy cell growth and energy balance. It activates other proteins that control cell metabolism, growth, and movement, helping prevent abnormal cell development. When LKB1 works properly, it supports tumor suppression and normal cellular functions. Mutations or changes in this gene can impair its functions, increasing the risk of certain cancers, notably in the lungs, pancreas, and other tissues. Overall, LKB1 plays a critical role in keeping cells functioning correctly and preventing uncontrolled growth.