Limit of Quantitation (LOQ)

The Limit of Quantitation (LOQ) is the smallest amount of a substance that a scientific test can reliably measure with confidence. It indicates the lowest level at which the substance’s quantity can be accurately detected and quantified, not just detected but measured precisely. This ensures that the results are trustworthy and meaningful. For example, in medical testing, the LOQ determines the lowest concentration of a drug or marker that can be confidently identified and measured in a sample, helping to ensure accurate diagnosis and monitoring.