Ligase chain reaction

Ligase Chain Reaction (LCR) is a laboratory technique used to detect specific DNA sequences, such as genetic mutations or pathogens. It works by repeatedly connecting short DNA fragments called probes to a target DNA strand. When the probes perfectly match the target sequence, an enzyme joins them together, creating a new DNA molecule. This process is repeated many times, amplifying the signal and making it easier to identify the presence of the target DNA. LCR is highly sensitive and precise, useful in medical diagnostics and genetic analysis for detecting small amounts of genetic material.