LIG3 (DNA Ligase III)

DNA Ligase III (LIG3) is an enzyme that plays a key role in maintaining the integrity of our genetic information. It functions by sealing gaps or nicks in the DNA strands, ensuring the DNA remains continuous and intact. LIG3 is particularly important in repairing damaged DNA, especially in the context of mitochondrial DNA (found in cell energy centers). It works together with other proteins to fix breaks caused by damage or stress, helping prevent mutations and supporting overall cell health. Its activity is essential for proper DNA maintenance and genomic stability.