Letterer-Siwe disease

Letterer-Siwe disease is a rare, aggressive form of a condition called Langerhans cell histiocytosis, where certain immune cells called Langerhans cells grow uncontrollably. This disorder mainly affects infants and young children, causing symptoms like skin rashes, fever, swollen lymph nodes, anemia, and bone problems. It can also damage organs such as the liver, spleen, and lungs. The condition results from abnormal immune cell activity leading to tissue damage and inflammation. Treatment often involves chemotherapy or other medications to control cell growth and manage symptoms. Prompt medical care is essential for the best outcomes.