KRAS (Kirsten Rat Sarcoma Viral Oncogene Homolog) Mutations

KRAS mutations involve changes in a gene that helps regulate cell growth and division. When mutated, the KRAS gene can become permanently active, causing cells to grow uncontrollably and potentially leading to cancer. These mutations are common in cancers like pancreatic, colorectal, and lung cancers. Understanding KRAS mutations helps doctors determine prognosis and choose targeted treatments, as some therapies are designed to specifically attack cancers with these genetic changes. Overall, KRAS mutations play a significant role in cancer development and influence treatment strategies.