Krabbe disease

Krabbe disease is a rare genetic disorder that affects the nervous system. It occurs when the body lacks an enzyme called galactocerebrosidase, leading to a buildup of certain fats in the brain and nerves. This buildup damages the protective covering of nerve fibers (myelin), disrupting communication between the brain and body. Symptoms often appear in infancy and may include irritability, muscle weakness, feeding problems, and developmental delays. Krabbe disease progresses quickly and can be life-threatening, as it severely impairs nerve function. It is inherited in an autosomal recessive pattern, meaning both parents must carry the faulty gene.