Ko

Ko, or the dissociation constant, measures how tightly a molecule like an antibody binds to its target, such as an antigen. A lower Ko indicates a stronger, more stable binding, meaning the molecules stay attached more readily. Conversely, a higher Ko signifies weaker binding and easier dissociation. It helps scientists understand and compare the effectiveness of molecules in medical tests, drug development, and biological research by quantifying their affinity for specific targets.