Kinetics of drug dissolution

The kinetics of drug dissolution describes how quickly a drug dissolves into body fluids, enabling absorption into the bloodstream. It depends on factors like the drug’s physical form, particle size, and the environment’s pH and temperature. Faster dissolution generally leads to quicker onset of effects, while slower dissolution can prolong action. This process is influenced by surface area (smaller particles dissolve faster), solubility, and the formulation's design. Understanding dissolution kinetics helps in developing effective medications with predictable and consistent therapeutic responses.