KCNH2 (Potassium Channel, Beta Subunit)

KCNH2 encodes a protein that forms a specialized potassium channel in the heart, known as hERG. These channels help regulate the electrical signals that control heartbeats. The "beta subunit" interacts with the main channel structure, influencing how effectively it functions. Proper operation of these channels ensures the heart rhythm remains steady. Mutations or abnormalities in KCNH2 can disrupt this process, potentially leading to irregular heart rhythms and increasing the risk of fainting or sudden cardiac events. Understanding KCNH2 is important for assessing certain inherited heart conditions and developing safer medications.