Kavalactone phytochemistry

Kavalactones are active compounds found in the kava plant, known for their calming effects. Chemically, they are specialized molecules called lactones, which have a lactone ring—a structure involving a cyclic ester. These compounds interact with brain receptors to promote relaxation and reduce anxiety. There are about 18 different kavalactones, each with unique effects and potency. They are fat-soluble, meaning they can be stored in fat tissues. The balance and concentration of these kavalactones in kava determine its overall effects and safety profile.