KAT (lysine acetyltransferases)

Lysine acetyltransferases (KATs) are enzymes that modify proteins by attaching an acetyl group to specific lysine amino acids. This process, called acetylation, often regulates how proteins function, interact, or where they are located in the cell. KATs play essential roles in controlling gene expression, DNA repair, and cellular activities by modifying histones (proteins around which DNA is wrapped) and other proteins. Their activity influences cell behavior and health, and abnormalities in KAT function can be linked to diseases like cancer and neurodegenerative disorders.