Image for John F. Crigler - Pediatric endocrinologist who discovered Crigler-Najjar syndrome

John F. Crigler - Pediatric endocrinologist who discovered Crigler-Najjar syndrome

John F. Crigler was a pediatric endocrinologist known for his research on metabolic disorders in children. He, along with his colleague Dr. William Najjar, identified Crigler-Najjar syndrome, a rare genetic disorder affecting the liver's ability to process bilirubin, a substance produced during the breakdown of red blood cells. This condition leads to high levels of bilirubin in the blood, causing jaundice and other health issues. Crigler's work has been essential in understanding this syndrome and improving the care and treatment of affected individuals.