Janeway's Theory

Janeway’s Immunological Theory emphasizes that the immune system is primarily activated by microbial molecules known as pathogen-associated molecular patterns (PAMPs). These PAMPs are detected by pattern recognition receptors on immune cells, which serve as the immune system's alarm signals. This recognition prompts the immune response, enabling the body to identify and fight off pathogens effectively. Essentially, Janeway’s theory highlights that the innate immune system is equipped with built-in sensors that recognize common features of microbes, initiating defense mechanisms essential for maintaining health.