
Janeway's model of innate immunity
Janeway’s model of innate immunity describes how our body's first line of defense recognizes and responds to pathogens. It emphasizes the role of immune cells equipped with pattern recognition receptors (PRRs) that identify common features of microbes, known as pathogen-associated molecular patterns (PAMPs). When these receptors detect PAMPs, they activate immune responses quickly to contain infections. This model highlights how innate immunity provides an immediate, broad-spectrum response, setting the stage for the adaptive immune system to develop a more targeted and lasting immunity. It underscores the importance of early detection in controlling infections.