JAK3 gene

JAK3 is a gene that provides instructions for making a protein called Janus kinase 3, which plays a key role in the immune system. This protein helps immune cells communicate and develop properly, especially those involved in fighting infections. If JAK3 doesn’t work correctly due to mutations, it can lead to immune system problems, making it harder for the body to defend against illnesses. JAK3 is part of a larger family of genes that control signals within cells, influencing immune responses and blood cell development.