IRP1 (Iron Regulatory Protein 1)

IRP1 (Iron Regulatory Protein 1) is a protein that helps maintain healthy iron levels in our cells. It does this by sensing iron availability and controlling how the body absorbs, stores, and releases iron. When iron is low, IRP1 activates, binding to specific RNA sequences to increase iron uptake and storage. When iron is abundant, IRP1 changes shape and stops binding, reducing iron absorption and release. This regulation ensures cells have enough iron for essential functions without excess, which can be harmful. IRP1 plays a crucial role in maintaining iron balance and overall cellular health.