Ion Channelopathies

Ion channelopathies are genetic disorders caused by mutations in the genes that encode ion channels—proteins that control the flow of charged particles like sodium, potassium, calcium, and chloride into and out of cells. These channels are vital for normal cell function, particularly in nerve signaling, muscle movement, and heart rhythm. When they don’t work properly, it can lead to various health issues, such as epilepsy, cardiac arrhythmias, or muscle disorders. These conditions are inherited and can affect specific tissues or systems, disrupting normal electrical activity and causing a range of symptoms depending on which channels are affected.