Investigator-initiated trial (IIT)

An Investigator-Initiated Trial (IIT) is a clinical research study designed and led by a healthcare professional or academic researcher rather than a pharmaceutical or biotech company. These trials often explore new uses for existing drugs, compare treatments, or investigate innovative approaches to patient care. IITs are driven by scientific questions and patient needs, with funding sometimes provided by government or academic sources. They aim to advance medical knowledge, improve treatment options, and contribute to evidence-based medicine, serving as a vital part of the research landscape outside of commercial interests.