Interleukin-28B (IL28B) gene

Interleukin-28B (IL28B) is a gene that produces a protein involved in the body's immune response to viral infections, particularly hepatitis C. This protein, part of the body's natural defense system, helps fight off viruses by activating immune cells. Variations in the IL28B gene can influence how well a person responds to hepatitis C treatment or clears the infection naturally. Understanding these genetic differences can help healthcare providers predict treatment success and personalize therapies, ultimately improving management of hepatitis C and related conditions.