Interferon-gamma Receptor Deficiency

Interferon-gamma receptor deficiency is a rare genetic condition where the body's immune system can't respond properly to interferon-gamma, a protein vital for fighting certain infections, especially those caused by bacteria like tuberculosis. Without this receptor working correctly, immune cells can't effectively activate other immune defenses, leading to increased vulnerability to specific infections. People with this deficiency may experience recurrent or severe infections and may require specialized medical care to manage their immune system's response to these threats.