Interference microscopy

Interference microscopy is a technique that uses the principles of light interference to enhance the visualization of tiny details in a sample, such as cells or materials. It works by splitting a beam of light into two paths: one reflected from the sample and another from a reference. When these light waves recombine, they create interference patterns that reveal subtle variations in the sample's structure and thickness. This method provides high-contrast, detailed images without needing dyes or stains, enabling scientists to observe and analyze transparent or delicate specimens with great precision.