IMPROVE-IT trial

The IMPROVE-IT trial was a large medical study testing whether adding a drug called ezetimibe to standard cholesterol treatment (statins) would better prevent heart attacks and related problems in people who recently experienced a heart attack or similar event. The trial found that the combination lowered bad cholesterol more effectively and slightly reduced the risk of future heart issues, showing that targeting different cholesterol pathways can improve patient outcomes. Overall, it provided important evidence supporting more aggressive cholesterol management in high-risk patients.