IgG anti-NMDA receptor antibodies

IgG anti-NMDA receptor antibodies are immune system proteins that mistakenly target and attack NMDA receptors in the brain, which are crucial for communication between nerve cells. This autoimmune response can disrupt normal brain functions, leading to symptoms such as psychiatric changes, seizures, movement disorders, and confusion. These antibodies are often associated with a condition called anti-NMDA receptor encephalitis, which is treatable with immune therapy. Detecting these antibodies in the blood or cerebrospinal fluid helps diagnose the condition and guide appropriate treatment.