IGF-binding proteins

IGF-binding proteins (IGFBPs) are specialized proteins that attach to insulin-like growth factors (IGFs), which are molecules that stimulate cell growth and development. By binding to IGFs, IGFBPs regulate their activity, controlling how much they can promote growth and when. They act like carriers, extending the lifespan of IGFs in the bloodstream, and can also influence how IGFs reach their target tissues. In this way, IGFBPs play a crucial role in coordinating growth, development, and energy use in the body.