IgE-Mediated Drug Allergies

IgE-mediated drug allergies occur when the immune system mistakenly identifies a medication as a harmful substance. This triggers an immune response involving Immunoglobulin E (IgE), a type of antibody. When the drug is encountered again, IgE antibodies cause the release of chemicals like histamine, leading to allergic symptoms such as hives, swelling, or difficulty breathing. These reactions can be immediate and potentially severe, such as anaphylaxis. Understanding this mechanism helps in diagnosing and managing drug allergies effectively, ensuring safer medication use in affected individuals.