Human Anti-Granulocyte Antibodies

Human Anti-Granulocyte Antibodies (HAGAs) are immune proteins produced by the body that mistakenly target and attack granulocytes, a type of white blood cell important for fighting infections. Normally, these antibodies help monitor and regulate the immune system. However, in some cases, HAGAs can cause problems such as lowering granulocyte levels, leading to increased risk of infections. They are often associated with conditions like autoimmune disorders or complications from certain treatments like stem cell transplants. Testing for HAGAs helps diagnose and manage these immune-related issues, guiding appropriate medical interventions.