HIF-3

HIF-3 is a type of hypoxia-inducible factor, which is a protein that helps cells respond to low oxygen levels. When oxygen is scarce, HIF-3 becomes active and influences the expression of genes involved in adapting to these conditions. Unlike other HIFs, HIF-3's role is less well understood, but it appears to regulate or fine-tune the activity of related factors, helping cells manage oxygen shortages more effectively. Its activity is important in processes like development, immune response, and potentially in diseases where oxygen supply is disrupted.